CovidV2, new, Analysis, bibRecord, 000139

Teicoplanin: an alternative drug for the treatment of coronavirus COVID-19?

Identifieur interne : 000139 ( new/Analysis ); précédent : 000138; suivant : 000140

Teicoplanin: an alternative drug for the treatment of coronavirus COVID-19?

Auteurs : Sophie Alexandra Baron [France] ; Christian Devaux [France] ; Philippe Colson [France] ; Didier Raoult [France] ; Jean-Marc Rolain [France]

Source :

International journal of antimicrobial agents [ 1872-7913 ] ; 2020.

RBID : pubmed:32179150

Abstract

In December 2019, a new coronavirus, named SARS-CoV-2, has emerged from China causing pneumonia outbreaks first in the Wuhan region and have now spread worldwide because of its probable high transmission efficiency. Due to the lack of efficient and specific treatments and the need to contain the epidemic, drug repurposing appears to be the best tool to find therapeutic solution. Chloroquine, remdesivir, lopinavir, ribavirin or ritonavir have shown efficacy to inhibit coronavirus in vitro. Teicoplanin, an antibiotic used to treat staphylococci infection, previously showed efficacy to inhibit the first stage of MERS-coronarivus viral cycle in human cells. This activity is conserved on the SARS-Cov-2, thus placing teicoplanin as a potential treatment for patients with this virus.

DOI: 10.1016/j.ijantimicag.2020.105944
PubMed: 32179150

Affiliations:

Links to Exploration step

pubmed:32179150

Le document en format XML

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Teicoplanin: an alternative drug for the treatment of coronavirus COVID-19?

Teicoplanin: an alternative drug for the treatment of coronavirus COVID-19?

Source :

Abstract

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